Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,606
Tocris Bioscience™ SW 033291
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High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
| Target | Dehydrogenase Inhibitors |
|---|---|
| CAS | 459147-39-8 |
| Purity | >98% |
| Chemical Name or Material | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H20N2OS3 |
| Formula Weight | 412.59 |
1,607
Tocris Bioscience™ CRBN-6-5-5-VHL
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Potent and selective cereblon Degrader (PROTAC™); cell-permeable
1,608
Tocris Bioscience™ Proglumide sodium salt
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CAS: 99247-33-3 Molecular Formula: C18H25N2NaO4
| CAS | 99247-33-3 |
|---|---|
| Molecular Formula | C18H25N2NaO4 |
1,609
Tocris Bioscience™ WZB 117
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GLUT inhibitor
| CAS | 1223397-11-2 |
|---|---|
| Chemical Name or Material | 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate) |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C20H13FO6 |
| Formula Weight | Observed MW: 368.31 |
| Assay Percent Range | >98% |
1,610
Tocris Bioscience™ Chroman 1
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Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogeneisis
| Target | Rho-kinase Inhibitors |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (3 S)-N-[2-[2-(Dimethylamino)ethoxy]-4-(1 H-pyrazol-4-yl)phenyl]-3,4-dihydro-6-methoxy-2 H-1-benzopyran-3-carboxamide dihydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H28N4O40.2 HCl |
1,611
Tocris Bioscience™ AEE 788
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Potent EGFR and VEGFR inhibitor
| Inhibitors | AEE 788 |
|---|---|
| Product Type | AEE 788 |
| Molecular Weight (g/mol) | 440.58 |
| Purity | >98% |
1,612
Tocris Bioscience™ BGC 20-1531 hydrochloride
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High affinity and selective EP4 antagonist
1,613
Tocris Bioscience™ CCCP
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CAS: 555-60-2 Molecular Formula: C9H5ClN4
| CAS | 555-60-2 |
|---|---|
| Molecular Formula | C9H5ClN4 |
1,614
Tocris Bioscience™ Aliskiren hemifumarate
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Potent renin inhibitor; antihypertensive
| Product Type | Aliskiren hemifumarate |
|---|---|
| Molecular Weight (g/mol) | 609.83 |
| Purity | >99% |
1,615
Tocris Bioscience™ EN6
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H+ ATPase activator; activates autophagy; inactivates mTORC1 signaling
| Target | H+-ATPase Inhibitors |
|---|---|
| CAS | 1808714-73-9 |
| Purity | 0.98 |
| Chemical Name or Material | N-[4-Fluoro-3-[(1-oxo-2-propen-1-yl)amino]phenyl]-1-(2-fluorophenyl)-1 H-pyrazole-4-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H14F2N4O2 |
1,616
Tocris Bioscience™ Ro 64-5229
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CAS: 246852-46-0 Molecular Formula: C17H19Cl2N3O
| CAS | 246852-46-0 |
|---|---|
| Molecular Formula | C17H19Cl2N3O |
1,617
Tocris Bioscience™ CNQX disodium salt
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CAS: 479347-85-8 Molecular Formula: C9H2N4Na2O4
| CAS | 479347-85-8 |
|---|---|
| Molecular Formula | C9H2N4Na2O4 |
1,618
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Tocris Bioscience™ CP 690550 citrate
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Tocris Bioscience™ CP 690550 citrate
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CAS: 540737-29-9 Molecular Formula: C22H28N6O8
| CAS | 540737-29-9 |
|---|---|
| Molecular Formula | C22H28N6O8 |
1,619
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Tocris Bioscience™ DMXAA
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Tocris Bioscience™ DMXAA
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mSTING agonist; induces antitumor immunological responses
| Target | STING Agonists |
|---|---|
| CAS | 117570-53-3 |
| Purity | 99% |
| Chemical Name or Material | 5,6-Dimethyl-9-oxo-9 H-xanthene-4-acetic acid |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C17H14O4 |
| Formula Weight | 282.29 |
1,620
Tocris Bioscience™ BMS 986187, >98%
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CAS: 684238-37-7 Molecular Formula: C31H34O4
| CAS | 684238-37-7 |
|---|---|
| Molecular Formula | C31H34O4 |